Dopa decarboxylase, 1-480 aa Human, His-tagged, Recombinant, E.coli

Dopa decarboxylase, also known as DDC, is a homodimeric, pyridoxal phosphate dependent enzyme. Dopa decarboxylase is a protein implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson’s disease.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	TP01914
Size	100 µg
Host	E.coli
Accession
Molecular Weight	56.4 kDa (503aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag
Sequences	MGSSHHHHHHSSGLVPRGSHTRSMNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
Purity	> 95% by HPLC
Concentration	1 mg/ml (determined by Bradford assay)
Formulation	Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT 10% glycerol.
Other Names	DDC, AADC, Aromatic L-amino acid decarboxylase, L-Dopa decarboxylase
Bioactivity
Storage	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript	For research use only, not for use in diagnostic procedures.

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Dopa decarboxylase, 1-480 aa Human, His-tagged, Recombinant, E.coli

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