STK3, 1-322aa, Human, His-tag, Baculovirus

Categories: [Proteins / Peptides]
STK3, also known as serine/threonine-protein kinase 3, is a mammalian Ste20-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. It is a serine/threonine kinase that functions early in a pheromone responsive signal transduction cascade in yeast. It activates the human large tumor suppressor kinase Lats1. It modulates stress-induced cardiac hypertrophy. Recombinant human STK3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP04066
Size 50 µg
Host Baculovirus
Accession
Molecular Weight 37.6kDa (331aa), 40-57kDa (SDS-PAGE under reducing conditions)
AP_Mol_Weight
Tag
Sequences ADPMEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDHHHHHH
Purity > 95% by HPLC
Concentration 0.25mg/ml (determined by Absorbance at 280nm)
Formulation Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Other Names Serine/threonine-protein kinase 3, STK3, KRS1, MST2
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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