DTD1, 1-209aa, Human, His tag, E.coli

重组人D-酪氨酰-tRNA脱酰酶1

DTD1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype.
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基本信息

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货号 TP01928
规格 20 µg
宿主 E.coli
Accession
分子大小 25.9kDa (232aa) confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
蛋白序列 MGSSHHHHHHSSGLVPRGSHMGSMKAVVQRVTRASVTVGGEQISAIGRGICVLLGISLEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKQYEILCVSQFTLQCVLKGNKPDFHLAMPTEQAEGFYNSFLEQLRKTYRPELIKDGKFGAYMQVHIQNDGPVTIELESPAPGTATSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNTPRKEDRSASSGAEGDVSSEREP
纯度 > 95% by HPLC
浓度 0.5 mg/ml (determined by Bradford assay)
配方 Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
别名 D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, pqn-68
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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