DCPS, 1-337aa, Human, His tag, E.coli

重组人清道夫脱帽酶/热休克蛋白1

DCPS, also known as scavenger mRNA-decapping enzyme, is belongs to the HIT family. It is necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. A scavenger decapping enzyme, DcpS was shown to hydrolyze the residual m7GpppN cap structure after the complete 3′–5′ degradation of the mRNA by the exosome.
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基本信息

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货号 TP01839
规格 50ug
宿主 E.coli
Accession
分子大小 40.8 kDa (357aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
蛋白序列 MGSSHHHHHHSSGLVPRGSHMADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS
纯度 > 95% by HPLC
浓度 0.5 mg/ml (determined by Bradford assay)
配方 Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
别名 Scavenger mRNA-decapping enzyme DcpS, DCS1, HINT5
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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