CREB3L2 is a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. This protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human CREB3L2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.