Anamorsin, also known as CIAPIN1, is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regulatory molecules of the Bcl-2 or CASP families, or to signal transduction molecules. Expression of CIAPIN1 is dependent on growth factor stimulation. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Recombinant human CIAPIN1protein, fused to His-tag at N-terminus, was expressed in E.coli.