CEACAM1, also known as carcinoembryonic antigen-related cell adhesion molecule 1 isoform 6, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. This protein is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses. Recombinant human CEACAM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.