CD68, also known as macrosialin, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is expressed on monocytes/macrophages. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.