Anti-Human/Mouse/Rat TSC22D3 Polyclonal Antibody

TSC22D3多克隆抗体

The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene. 
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基本信息

数据文档 查看数据文档
货号 PA12058
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human TSC22D3
特异性 Expressed in brain, lung, spleen and skeletal muscle. Lower levels detected in heart and kidney. Not detected in the pancreas. In non-lymphoid tissues, in the absence of inflammation, the major source of constitutive expression is the macrophage lineage. Also expressed in cells from different hemopoietic cell lineages, including bone marrow cells, CD34+ stem cells, mature B- and T-cells, monocytes and granulocytes. Down-regulated in activated macrophages from inflammatory lesions of delayed-type hypersensitivity (DTH) reactions, such as in tuberculosis and in Crohn disease, whereas in Burkitt lymphoma, persists in macrophages involved in the phagocytosis of apoptotic malignant cells.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q99576
浓度 0.6 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 Delta sleep-inducing peptide immunoreactor,DIP,DSIP immunoreactive leucine zipper protein,DSIP-immunoreactive peptide,Dsip1,Dsipi,GILZ,Glucocorticoid-induced leucine zipper protein,hDIP,Protein DIP,T22D3,TSC-22-like protein,TSC-22-related protein,TSC-22R,TSC22 domain family protein 3,TSC22 domain family,member 3,TSC22 related inducible leucine zipper 3,TSC22D3
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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