Anti-Human/Mouse/Rat Phospho-EPOR (Tyr368) Polyclonal Antibody

Phospho-EPOR (Tyr368)多克隆抗体

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
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基本信息

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货号 PA01742
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human EpoR around the phosphorylation site of Tyr368
特异性 Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early-stage erythroid progenitor cells.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P19235
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:10000
配方
应用范围 WB,IF,ELISA
别名 EPO R,EPO-R,epor,EPOR,Erythropoietin receptor,Erythropoietin receptor precursor,MGC138358
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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