Anti-Human/Mouse/Rat/Monkey Phospho-YAP1 (Ser127) Polyclonal Antibody

Phospho-YAP1 (Ser127)多克隆抗体

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
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基本信息

数据文档 查看数据文档
货号 PA01806
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human YAP around the phosphorylation site of Ser127
特异性 Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level).
亚型 IgG
反应性 Human,Mouse,Rat,Monkey
克隆
Uniprot P46937
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
配方
应用范围 WB,IHC-p,ELISA
别名 65 kDa Yes associated protein,65 kDa Yes-associated protein,COB1,YAp 1,YAP 65,YAP,YAP1,YAP1,YAP2,YAP65,yes -associated protein delta,Yes associated protein 1 65kDa,Yes associated protein 1,Yes associated protein 2,yes associated protein beta,YKI,Yorkie homolog
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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