Anti-Human/Mouse/Rat HSP40-4 Polyclonal Antibody

HSP40-4多克隆抗体

DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
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基本信息

数据文档 查看数据文档
货号 PA12016
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human DNAJA1
特异性 Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P31689
浓度 0.2 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 DJ 2,DJ2,DjA1,DnaJ (Hsp40) homolog,subfamily A,member 1,DnaJ homolog subfamily A member 1,DnaJ protein homolog 2,DNAJ2,Dnaja1,DNJA1,hDJ 2,HDJ-2,HDJ2,Heat shock 40 kDa protein 4,heat shock protein DNAJ like 2,Heat shock protein J2,HSDJ,HSJ-2,HSJ2,HSPF4,Human DnaJ protein 2,NEDD7,Neural precursor cell expressed developmentally down regulated 7,OTTHUMP00000021193
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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