Anti-Human/Mouse/Monkey Phospho-BLNK (Tyr96) Polyclonal Antibody

Phospho-BLNK (Tyr96)多克隆抗体

Functions as a central linker protein that bridges kinases associated with the B-cell receptor (BCR) with a multitude of signaling pathways, regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition (By similarity). Plays an important role in BCR-induced B-cell apoptosis.
价格: 2507.4元
  • Buy 5 for ¥2382.03 each and save 5%
  • Buy 21 for ¥2256.66 each and save 10%
  • Buy 31 for ¥2131.29 each and save 15%
  • Buy 51 for

基本信息

数据文档 查看数据文档
货号 PA01801
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human BLNK around the phosphorylation site of Y96.
特异性 Expressed in B-cell lineage and fibroblast cell lines (at protein level). Highest levels of expression in the spleen, with lower levels in the liver, kidney, pancreas, small intestines and colon.
亚型 IgG
反应性 Human,Mouse,Monkey
克隆
Uniprot Q8WV28
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 AGM4,B cell adapter containing SH2 domain protein,B cell adapter containing Src homology 2 domain protein,B cell adaptor containing SH2 domain,B cell linker,B cell linker protein,B cell-specific adaptor protein,B-cell activation,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,B-cell linker protein,BASH,Bca,BLNK,BLNK s,BLNK,Cytoplasmic adapter protein,Ly 57,Ly57,Lymphocyte antigen 57,Lyw 57,Lyw57,MGC111051,SH2 domain-containing leukocyte protein,65-KD,SLP 65,SLP-65,SLP65,Src homology [SH2] domain-containing leukocyte protein of 65 kD,Src homology 2 domain containing leukocyte protein of 65 kDa,Src homology 2 domain-containing leukocyte protein of 65 kDa
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

©2024 武汉天正源生物科技有限公司版权所有. SiteMap