Anti-Human CYP4F2 Polyclonal Antibody

CYP4F2多克隆抗体

CYP4F2 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) is a Protein Coding gene. Diseases associated with CYP4F2 include Cyp4f2-Related Altered Drug Metabolism and Vitamin K Antagonists Toxicity Or Dose Selection. Among its related pathways are Cytochrome P450 - arranged by substrate type and Arachidonic acid metabolism. GO annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP4F3.
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基本信息

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货号 PA03423
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the N-terminal region of human CYP4F2
特异性 Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572).
亚型 IgG
反应性 Human
克隆
Uniprot P78329
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
配方
应用范围 WB,IHC-p,ELISA
别名 Cyp4f14,CYPIVF1,Cytochrome P450 LTB omega,Cytochrome P450,family 4,subfamily F,polypeptide 2,EC 1.14.14.1,Leukotriene B(4) 20 monooxygenase,Leukotriene B(4) omega hydroxylase,MGC126966,MGC93476,P450 A3
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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