ALKBH3, 1-286aa, Human, His tag, E.coli

人α酮戊二酸依赖性双加氧酶alkB类似物3(1-286aa)重组蛋白

ALKBH3 is a member of the ALKB family of proteins and functions as a dioxygenase with a preference for RNA and single stranded DNA substrates. This protein repairs 1-methyladenine and 3- methylcytosine lesions in alkylated DNA and RNA and its activity is stimulated by ascorbate.
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基本信息

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货号 TP01140
规格 100 µg
宿主 E.coli
Accession
分子大小 37.9 kDa (325aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
蛋白序列 MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSELDMEEKRRRARVQGAWAAPVKSQAIAQPATTAKSHLHQKPGQTWKNKEHHLSDREFVFKEPQQVVRRAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLCQDVPWKQRTGIREDITYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW
纯度 > 95% by HPLC
浓度 1 mg/ml (determined by Bradford assay)
配方 Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
别名 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, ABH3, DEPC-1, DEPC1, PCA1.
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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