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Anti-Human UBE2C Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
UBE2C(Ubiquitin-conjugating enzyme E2 C) is also known as UBCH10 and belongs to the ubiquitin-conjugating enzyme family. It is highly expressed in a variety of human primary tumors,and it is able to promote cell proliferation and malignant transformation. UBE2C,along with the E3 ligase of the anaphasepromoting complex (APC),catalyzes the ubiquitination of mitotic cyclins A and B,as well as securin. UBE2C is essential for cell cycle progression,and mutation of its active site cysteine confers a dominant-negative phenotype.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02172
Size 100μl
Host Type Mouse
Immunogen Fusion protein of UBE2C
Specificity
Isotype IgG1
Reacitivity Human
Clone 230
Uniprot O00762
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200, IF 1:10-1:100
Formulation
Application WB,IHC,IF,ELISA
Other Names Cyclin selective ubiquitin carrier protein,dJ447F3.2,Mitotic specific ubiquitin conjugating enzyme,UB E2C,UBCH 10,UbcH10,UBE 2C,Ube2c,UBE2C,Ubiquitin carrier protein C,Ubiquitin carrier protein E2 C,Ubiquitin carrier protein E2C,Ubiquitin conjugating enzyme E2 C,Ubiquitin conjugating enzyme E2C,Ubiquitin protein ligase C,Ubiquitin-conjugating enzyme E2 C,Ubiquitin-protein ligase C
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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