Anti-Human TPSAB1 Monoclonal Antibody

TPSAB1(Tryptase alpha/beta-1) is also named as TPS1,TPS2,TPSB1 and belongs to the peptidase S1 family. It is the major neutral protease present in mast cells and secreted upon the coupled activation-degranulation response of this cell type. TPSAB1 has 2 isoforms produced by alternative splicing with the molecular weight of 31 kDa and 29 kDa. This full length protein has two glycosylation sites.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02161
Size 100μl
Host Type Mouse
Immunogen Fusion protein of TPSAB1
Specificity Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level).
Isotype IgG1
Reacitivity Human
Clone 790
Uniprot Q15661
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names alpha II,Lung tryptase,Mast cell alpha II tryptase,Mast cell beta I tryptase,Mast cell protease 7,Mast cell protease II,MCP 7,Pituitary tryptase,Skin tryptase,TPS 1,TPS1,TPS2,TPSAB1,TPSAB1 protein,TPSB1,Tryptase 1,Tryptase alpha 1,tryptase alpha I included,Tryptase alpha II,tryptase alpha II included,tryptase alpha included,tryptase alpha/beta 1,Tryptase beta 1,tryptase beta I included,Tryptase I,tryptase I included,Tryptase III,Tryptase skin
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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