Anti-Human TMEM106B Monoclonal Antibody

TMEM106B is a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS),like FTLD-TDP,is characterized by pathological TDP-43 inclusions. TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confer genetic susceptibility by increasing gene expression.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02154
Size 100μl
Host Type Mouse
Immunogen Fusion protein of TMEM106B
Specificity Expressed in frontal cortex.
Isotype IgG1
Reacitivity Human
Clone 123
Uniprot Q9NUM4
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names 2310036D22Rik,5830455K21Rik,6430519M21Rik,AI428776,AI661344,FLJ11273,LRRGT00101,MGC33727,MGC94135,T106B,Tmem106b,Transmembrane protein 106B
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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