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Anti-Human TLE3 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
TLE3,also named as KIAA1547 and ESG3,belongs to the WD repeat Groucho/TLE family. It is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE3 is a member of the transducin-like enhancer of split (TLE) family of proteins that have been implicated in the tumorgenesis and classification of sarcomas. It is a candidate biomarker of response to taxane therapy.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02153
Size 100μl
Host Type Mouse
Immunogen Fusion protein of TLE3
Specificity Placenta and lung.
Isotype IgG1
Reacitivity Human
Clone 654
Uniprot Q04726
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names E(sp1) homolog Drosophila,Enhancer of split groucho 3,Enhancer of split groucho-like protein 3,ESG 3,ESG,ESG3,FLJ39460,GRG 3,GRG3,HsT18976,KIAA1547,TLE 3,Tle3,TLE3,Transducin like enhancer of split 3,Transducin like enhancer of split 3 homolog of Drosophila E(sp1),Transducin like enhancer protein 3,transducin-like enhancer of split 3 (E(sp1) homolog,Drosophila),Transducin-like enhancer protein 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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