Anti-Human SERPINA3 Polyclonal Antibody

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12979
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human SERPINA3
Specificity Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.
Isotype IgG
Reacitivity Human
Clone
Uniprot P01011
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names SERPINA3,AACT,AACT,ACT,Alpha-1-antichymotrypsin His-Pro-less,Antichymotrypsin,Cell growth inhibiting gene 24/25 protein,Cell growth-inhibiting gene 24/25 protein,GIG24,GIG25,Growth inhibiting protein 24,Growth inhibiting protein 25,MGC88254,Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase,antitrypsin) member 3,Serine (or cysteine) proteinase inhibitor clade A member 3,Serine proteinase inhibitor clade A member 3,Serpin A3,Serpin family A member 3,Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3,SERPINA3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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