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Anti-Human PTPRN Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01997
Size 100μl
Host Type Mouse
Immunogen Fusion protein of IA-2/PTPRN
Specificity Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
Isotype IgG3
Reacitivity Human
Clone 94
Uniprot Q16849
Concentration None
Dilution WB 1:200-1:2000, IHC 1:200-1:800, IF 1:10-1:100
Formulation
Application WB,IHC,IF,ELISA
Other Names CA 512,FLJ16131,IA 2,IA 2/PTP,IA2,IA2/PTP,ICA 3,ICA 512,ICA3,ICA512,Islet cell antigen 2,Islet cell antigen 512,Islet cell autoantigen 3,Protein tyrosine phosphatase like N,Protein tyrosine phosphatase like N precursor,Protein tyrosine phosphatase receptor type N,PTP IA 2,PTP IA-2,PTP IA2,PTPIA 2,PTPN,Ptprn,PTPRN protein,PTPRN,R PTP N,R-PTP-N,Receptor type tyrosine protein phosphatase like N,Receptor-type tyrosine-protein phosphatase-like N,RPTPN
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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