Anti-Human PDCD4 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]

Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation,progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA02080
Size	100μl
Host Type	Mouse
Immunogen	Fusion protein of PDCD4
Specificity	Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Isotype	IgG1
Reacitivity	Human
Clone	911
Uniprot	Q53EL6
Concentration	None
Dilution	WB 1:1000-1:10000, IHC 1:20-1:200
Formulation
Application	WB,IHC,ELISA
Other Names	Death up-regulated gene protein,Dug,H731,Ma3,MGC33046,MGC33047,Neoplastic transformation inhibitor,Neoplastic transformation inhibitor protein,Nuclear antigen H731,Nuclear antigen H731 like,Nuclear antigen H731 like protein,Nuclear antigen H731-like,PDCD 4,Pdcd4,PDCD4,Programmed cell death 4,programmed cell death 4 (neoplastic transformation inhibitor),Programmed cell death protein 4,Protein 197/15a,Protein MA-3,Tis,Topoisomerase-inhibitor suppressed protein
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human PDCD4 Monoclonal Antibody

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