Anti-Human P-Selectin Monoclonal Antibody

P-selectin,also known as GMP140 or CD62P,is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation,thrombosis,and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists,P-selectin is transported rapidly to the cell surface.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02100
Size 100μl
Host Type Mouse
Immunogen Fusion protein of P-selectin
Specificity Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Isotype IgG2b
Reacitivity Human
Clone 756
Uniprot P16109
Concentration None
Dilution WB 1:200-1:2000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names Antigen CD62,CD62,CD62 antigen-like family member P,CD62P,GMP 140,GMP-140,GMP140,GMRP,Granule membrane protein 140,Granulocyte membrane protein,GRMP,LECAM 3,LECAM3,Leukocyte endothelial cell adhesion molecule 3,Leukocyte-endothelial cell adhesion molecule 3,LYAM3,P Selectin,P-selectin,PADGEM,Platelet activation dependent granule-external membrane protein,Platelet alpha granule membrane protein,PSEL,Selectin P (granule membrane protein 140kDa,antigen CD62),SELP
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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