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Anti-Human NOB1 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
NOB1 was first identified in yeast as an essential gene encoding the Nin one binding protein,which is involved in pre-rRNA processing. In a late cytoplasmic processing step,Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA. In addition,NOB1 is a crucial molecule in the maturation of the 20S proteasome and protein degradation. It serves as a chaperone to join the 20S proteasome with the 19S regulatory particle in the nucleus and facilitates the maturation of the 20S proteasome. Recently NOB1 has been reported to be overexpressed in several types of cancer,suggesting its involvement in the tumorigenesis.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02058
Size 100μl
Host Type Mouse
Immunogen Fusion protein of NOB1
Specificity Detected in liver, lung, placenta, endothelial cells and spleen.
Isotype IgG1
Reacitivity Human
Clone 7790
Uniprot Q9ULX3
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names Adenocarcinoma antigen recognized by T lymphocytes 4,ART 4,ART4,MST158,MSTP158,Nin one binding protein,NIN1/PSMD8 binding protein 1 homolog,NIN1/RPN12 binding protein 1 homolog (S. cerevisiae),nob1,NOB1,NOB1P,Phosphorylation regulatory protein HP-10,Protein ART-4,Protein ART4,PSMD8 binding protein 1,PSMD8BP1,RNA binding protein NOB1,RNA-binding protein NOB1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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