Anti-Human NKX2-1 Monoclonal Antibody

Homeobox protein Nkx-2.1 (NKX2-1),also named Thyroid nuclear factor 1,Thyroid transcription factor 1(TTF1). It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase,and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC),choreoathetosis,hypothyroidism,and neonatal respiratory distress (CHNRD).
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02169
Size 100μl
Host Type Mouse
Immunogen Synthetic Peptide
Specificity Thyroid and lung.
Isotype IgG3
Reacitivity Human
Clone 654
Uniprot P43699
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names AV026640,BCH,Benign chorea,BHC,Homeobox protein NK 2 homolog A,Homeobox protein NK-2 homolog A,Homeobox protein Nkx 2.1,Homeobox protein Nkx-2.1,Homeobox protein Nkx2.1,NK 2,NK 2 homolog A,NK2,NK2 homeobox 1,NK2,drosophila,homolog of,A,NK2.1,mouse,homolog of,Nkx 2 1,NKX 2.1,NKX 2A,NKX2 1,Nkx2-1,NKX2.1,NKX21,NKX2A,T EBP,T/EBP,TEBP,Thyroid nuclear factor 1,Thyroid nuclear factor,Thyroid specific enhancer binding protein,Thyroid transcription factor 1,Tin man,Tinman,TITF 1,TITF1,TTF 1,TTF-1,TTF1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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