Anti-Human/Mouse Zap70 Monoclonal Antibody

Zeta-associated protein (ZAP)-70,a member of the Syk family of tyrosine kinases,plays an important role in T-cell receptor signaling,natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02183
Size 100μl
Host Type Mouse
Immunogen Fusion protein of ZAP70
Specificity Isoform 1 and isoform 2 are expressed in thymus, spleen and lymph nodes.1 Publication
Isotype IgG1
Reacitivity Human,Mouse
Clone 76
Uniprot P43404
Concentration None
Dilution WB 1:500-1:5000
Formulation
Application WB,ELISA
Other Names 70 kDa zeta associated protein,70 kDa zeta-associated protein,EC 2.7.10.2,FLJ17670,FLJ17679,Selective T cell defect,SRK,STD,Syk related tyrosine kinase,Syk-related tyrosine kinase,Truncated ZAP kinase,Tyrosine protein kinase ZAP70,Tyrosine-protein kinase ZAP-70,TZK,ZAP 70,ZAP70,ZAP70,Zeta chain associated protein kinase 70kD,Zeta chain associated protein kinase 70kDa,Zeta chain associated protein kinase 70kDa isoform 1,Zeta chain associated protein kinase 70kDa isoform 2,Zeta chain of T cell receptor associated protein kinase 70,Zeta chain TCR associated protein kinase 70kD,Zeta chain TCR associated protein kinase 70kDa
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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