Anti-Human/Mouse XRCC6 Polyclonal Antibody

The p70/p80 autoantigen is a nuclear complex consisting of two subunits witHuman, Mouseolecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12398
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human XRCC6
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P12956
Concentration 0.3 mg/mL
Dilution IHC 1:10-1:50
Formulation
Application IHC,ELISA
Other Names 5''-deoxyribose-5-phosphate lyase Ku70,5''-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP dependent DNA helicase 2 subunit 1,ATP dependent DNA helicase II 70 kDa subunit,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box binding factor 75 kDa subunit,CTC box-binding factor 75 kDa subunit,CTC75,CTCBF,DNA repair protein XRCC6,G22P1,Ku 70,Ku autoantigen p70 subunit,Ku autoantigen,70kDa,Ku p70,Ku70,Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa,Kup70,Lupus Ku autoantigen protein p70,ML8,Thyroid autoantigen 70kD (Ku antigen),Thyroid autoantigen,Thyroid lupus autoantigen,Thyroid lupus autoantigen p70,Thyroid-lupus autoantigen,TLAA,X ray repair complementing defective repair in Chinese hamster cells 6,X-ray repair complementing defective repair in Chinese hamster cells 6,X-ray repair cross-complementing protein 6,XRCC 6,Xrcc6,XRCC6
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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