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Anti-Human/Mouse TP53BP2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12556
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human TP53BP2
Specificity Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. Reduced expression in breast carcinomas expressing a wild-type TP53 protein. Overexpressed in lung cancer cell lines.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q13625
Concentration 0.5 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names 53BP2,Apoptosis stimulating of p53 protein 2,Apoptosis stimulating protein of p53 2,Apoptosis-stimulating of p53 protein 2,ASPP2,ASPP2,BBP,Bcl2 binding protein,Bcl2-binding protein,NY REN 51 antigen,p53 binding protein 2,p53-binding protein 2,p53BP2,PPP1R13A,Renal carcinoma antigen NY-REN-51,Tp53bp2,Tumor protein p53 binding protein 2,Tumor suppressor p53 binding protein 2,Tumor suppressor p53-binding protein 2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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