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Anti-Human/Mouse SRPX2 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
SRPX2 (sushi-repeat-containing protein,X-linked 2) is a secreted protein expressed in neurons of the human adult brain,including the rolandic area . Firstly described as sushi-repeat protein up-regulated in leukemia (SPRUL) in leukemia cells with dysregulated expression at the transcriptional level,SRPX2 has been recently shown as a multifunctional protein. SRPX2 is a ligand for uPAR,the urokinase-type plasminogen activator (uPA) receptor . It is involved in seizure disorders,angiogenesis and cellular adhesion . The involvement of SRPX2 in disorders of language cortex and cognition suggests it has an important role in the perisylvian region critical for language and cognitive development .
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02139
Size 100μl
Host Type Mouse
Immunogen Fusion protein of SRPX2
Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus and adrenal gland. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines.
Isotype IgG2b
Reacitivity Human,Mouse
Clone 657
Uniprot O60687
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500, IF 1:50-1:500
Formulation
Application WB,IHC,IF,ELISA
Other Names BPP,CBPS,PMGX,RESDX,SRPUL,SRPX 2,SRPX2,SRPX2,Sushi repeat containing protein SRPX2,Sushi repeat containing protein X linked 2,Sushi repeat protein,Sushi repeat-containing protein SRPX2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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