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Anti-Human/Mouse RNF7 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11764
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human RNF7
Specificity Expressed in heart, liver, skeletal muscle and pancreas. At very low levels expressed in brain, placenta and lung.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9UBF6
Concentration 0.2 mg/mL
Dilution WB 1:200-1:1000, IHC 1:10-1:50
Formulation
Application WB,IHC,ELISA
Other Names CKBBP 1,CKBBP1,CKII beta binding protein 1,CKII beta-binding protein 1,Rbx 2,Rbx2,RBX2,Regulator of cullins 2,RING box protein 2,RING finger protein 7,RING-box protein 2,RNF 7,RNF7,ROC 2,ROC2,SAG,Sensitive to apoptosis gene,Sensitive to apoptosis gene protein,Zinc RING finger protein SAG
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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