Anti-Human/Mouse/Rat XPO1 Polyclonal Antibody

The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12641
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human XPO1
Specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Not expressed in the kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O14980
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Chromosome region maintenance 1 protein homolog,CRM 1,CRM1 homolog,DKFZp686B1823,emb,Exp 1,Exp1,Exportin 1,Exportin-1,Exportin1,XPO 1,xpo1,XPO1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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