Anti-Human/Mouse/Rat TNNI3 Polyclonal Antibody

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11669
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human TNNI3
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P19429
Concentration 0.2 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names cardiac muscle,Cardiac troponin I,cardiomyopathy,dilated 2A (autosomal recessive),Cardiomyopathy,familial hypertrophic,7,included,CMD1FF,CMD2A,CMH7,cTnI,Familial hypertrophic cardiomyopathy 7,MGC116817,RCM1,Tn1,Tni,TNN I3,TNNC 1,TNNC1,TNNI3,TNNI3,Troponin I,Troponin I cardiac,Troponin I cardiac muscle,Troponin I cardiac muscle isoform,Troponin I type 3 cardiac,troponin I,cardiac 3,TroponinI,Ttroponin I type 3 (cardiac)
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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