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Anti-Human/Mouse/Rat PPARGC1A Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
PPARGC1A,also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,is a 798 amino acid protein,which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02542
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of PPARGC1A
Specificity Heart, skeletal muscle, liver and kidney. Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue. In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects.
Isotype IgG1
Reacitivity Human,Mouse,Rat
Clone 1C1B2
Uniprot Q9UBK2
Concentration None
Dilution WB 1:1000-1:10000, IF 1:50-1:500
Formulation
Application WB,IF,ELISA
Other Names L PGC 1alpha,LEM6,Ligand effect modulator 6,Peroxisome proliferative activated receptor gamma coactivator 1 alpha,Peroxisome proliferative activated receptor gamma coactivator 1,Peroxisome proliferator activated receptor gamma coactivator 1 alpha,Peroxisome proliferator activated receptor gamma coactivator 1 alpha transcript variant B4 3ext,Peroxisome proliferator activated receptor gamma coactivator 1 alpha transcript variant B4 8a,Peroxisome proliferator activated receptor gamma coactivator 1 alpha transcript variant B4,Peroxisome proliferator activated receptor gamma coactivator 1 alpha transcript variant B5,Peroxisome proliferator activated receptor gamma coactivator 1 alpha transcript variant B5 NT,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,PGC 1 (alpha),PGC 1 alpha,PGC 1v,PGC-1-alpha,PGC1,PGC1(alpha),PGC1A,PGC1v,PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6,PPAR gamma coactivator 1 alpha,PPAR gamma coactivator 1,PPAR gamma coactivator variant form,PPAR-gamma coactivator 1-alpha,PPARGC 1 alpha,PPARGC-1-alpha,PPARGC1,PPARGC1A,PRGC1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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