Anti-Human/Mouse/Rat Phospho-HDAC8 (Ser39) Polyclonal Antibody

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01567
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39
Specificity Weakly expressed in most tissues. Expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9BY41
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names CDA07,CDLS5,HD 8,HD8,HDAC 8,Hdac8,HDAC8,HDACL 1,HDACL1,Histone deacetylase 8,Histone deacetylase like 1,MRXS6,RPD 3,RPD3,WTS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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