Anti-Human/Mouse/Rat Phospho-EIF4E (Ser209) Polyclonal Antibody

Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01550
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human eIF4E around the phosphorylation site of Ser209
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P06730
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names AUTS19,CBP,eIF 4E,eIF 4F 25 kDa subunit,EIF 4F,eIF-4E,eIF-4F 25 kDa subunit,eIF4E,EIF4E1,EIF4EL1,EIF4F,Eukaryotic translation initiation factor 4 E,Eukaryotic translation initiation factor 4E,Eukaryotic translation initiation factor 4E like 1,IF4E,Messanger RNA Cap Binding Protein eIF 4E,MGC111573,mRNA cap binding protein,mRNA cap-binding protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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