Anti-Human/Mouse/Rat Phospho-DOK1 (Tyr362) Polyclonal Antibody

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01542
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Dok-1 around the phosphorylation site of Tyr362
Specificity Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q99704
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IF,ELISA
Other Names Docking protein 1 62kD,Docking protein 1,DOK 1,DOK1,DOK1,Downstream of tyrosine kinase 1,p62(dok),P62DOK,pp62
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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