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Anti-Human/Mouse/Rat Phospho-CD44 (Ser706) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01673
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human CD44 around the phosphorylation site of Ser706
Specificity Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P16070
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names LHR,BA-1,CD 44,CD44,CD44 antigen,CD44 molecule (Indian blood group),CD44 molecule,CD44,CDw44,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH-I,HUTCH1,Hyaluronate receptor,IN,INLU-related p80 Glycoprotein,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH1,PGP-1,PGP-I,PGP1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,Soluble CD44
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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