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Anti-Human/Mouse/Rat PHB2 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
PHB2,also named as BAP,REA,D-prohibitin,BAP37 and Prohibitin-2,belongs to the prohibitin family. It acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. PHB2 functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. PHB2 is probably involved in regulating mitochondrial respiration activity and in aging.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02543
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of Prohibitin 2
Specificity
Isotype IgG1
Reacitivity Human,Mouse,Rat
Clone 1D9C7
Uniprot Q99623
Concentration None
Dilution WB 1:5000-1:10000, IHC 1:50-1:500, IF 1:50-1:500
Formulation
Application WB,IHC,IF,ELISA
Other Names B cell receptor associated protein BAP37,B-cell receptor-associated protein BAP37,BAP,Bap37,BCAP 37,D prohibitin,D-prohibitin,p22,Phb2,PHB2,PNAS 141,Prohibitin 2,Prohibitin-2,Repressor of estrogen receptor activity
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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