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Anti-Human/Mouse/Rat PGP 9.5 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene .
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02173
Size 100μl
Host Type Mouse
Immunogen Fusion protein of UCHL1
Specificity Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
Isotype IgG1
Reacitivity Human,Mouse,Rat
Clone 346
Uniprot P09936
Concentration None
Dilution WB 1:1000-1:50000, IHC 1:200-1:2000, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names Epididymis luminal protein 117,Epididymis secretory protein Li 53,HEL 117,HEL S 53,NDGOA,Neuron cytoplasmic protein 9.5,OTTHUMP00000218137,OTTHUMP00000218139,OTTHUMP00000218140,OTTHUMP00000218141,Park 5,PARK5,PGP 9.5,PGP9.5,PGP95,Protein gene product 9.5,Ubiquitin C terminal esterase L1,Ubiquitin C terminal hydrolase,Ubiquitin C terminal hydrolase L1,Ubiquitin carboxyl terminal esterase L1,Ubiquitin carboxyl terminal hydrolase isozyme L1,Ubiquitin carboxyl-terminal hydrolase isozyme L1,Ubiquitin thioesterase L1,Ubiquitin thiolesterase,Ubiquitin thiolesterase L1,UCH-L1,UCHL1,UCHL1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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