Anti-Human/Mouse/Rat PARD6A Polyclonal Antibody

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12565
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human PARD6A
Specificity Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9NPB6
Concentration 0.7 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names 0710008C04Rik,2610010A15Rik,Par 6 partitioning defective 6 C elegans homolog alpha,Par 6 partitioning defective 6 homolog alpha,Par 6 partitioning defective 6 homolog alpha C elegans,PAR 6A,PAR-6 alpha,PAR-6,par-6 family cell polarity regulator alpha,PAR-6A,PAR6,PAR6A,PAR6alpha,PAR6C,Pard6a,Partitioning defective 6 homolog alpha,partitioning-defective protein 6,partitioning-defective protein 6, C. elegans,homolog of,alpha,Tax interacting protein 40,Tax interaction protein 40,TAX40,TIP 40,TIP-40,TIP40
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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