Anti-Human /Mouse /Rat MYOC Polyclonal Antibody

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03173
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human MYOC
Specificity Expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Expressed predominantly in the retina. In normal eyes, found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma.
Isotype IgG
Reacitivity Human ,Mouse ,Rat
Clone
Uniprot Q99972
Concentration 2.55 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB
Other Names GLC1A,GPOA,JOAG,JOAG1,Mutated trabecular meshwork-induced glucocorticoid response protein,MYOC,MYOC,Myocilin,Myocilin,trabecular meshwork inducible glucocorticoid,TIGR,Trabecular meshwork induced glucocorticoid response protein,Trabecular meshwork-induced glucocorticoid response protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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