Anti-Human/Mouse/Rat Fibulin 5 Monoclonal Antibody

Fibulin-5,also known as EVEC and DANCE,is a extracellular matrix glycoprotein,secreted by various cell types such as vascular smooth muscle cells,fibroblasts and endothelial cells. Structurally,Fibulin-5 contains an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. FBLN5 mutations have been described in patients with age-related macular degeneration,as well as being involved in Charcot-Marie-Tooth neuropathies.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01973
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Fibulin 5
Specificity Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes.
Isotype IgG1
Reacitivity Human,Mouse,Rat
Clone 937
Uniprot Q9UBX5
Concentration None
Dilution WB 1:1500-1:5000, IF 1:50-1:100
Formulation
Application WB,IHC,IF,ELISA
Other Names ADCL2,ARCL1A,ARMD3,Dance,Developmental arteries and neural crest EGF like protein,Developmental arteries and neural crest EGF-like protein,EVEC,Fbln5,FBLN5,FIBL 5,FIBL-5,Fibulin-5,FLJ90059,UP50,Urine p50 protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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