Anti-Human/Mouse/Rat ECE1 Polyclonal Antibody

The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12148
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ECE1
Specificity All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P42892
Concentration 0.7 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names ECE 1,ECE,ECE-1,ECE1,ECE1,Endothelin converting enzyme 1,Endothelin-converting enzyme 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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