Anti-Human/Mouse/Rat COLEC12 Polyclonal Antibody

This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02796
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human COLEC12
Specificity Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes and in perivascular astrocytes associated with cerebral amyloid angiopathy (CAA) in the temporal cortex of Alzheimer patient (at protein level). Strongly expressed in placenta. Moderately expressed in heart, skeletal muscle, small intestine and lung. Weakly expressed in brain, colon, thymus and kidney. Expressed in nurse-like cells. Expressed in reactive astrocytes and vascular/perivascular cells in the brain of Alzheimer patient.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q5KU26
Concentration 1.1 mg/mL
Dilution IHC 1:30-150, ELISA 1:2000-10000
Formulation
Application IHC,ELISA
Other Names CL P1,CL-P1,CLP1,COL12,COLEC 12,colec12,Collectin placenta 1,Collectin placenta protein 1,Collectin sub family member 12,Collectin-12,hCL P1,hCL-P1,NSR2,Nurse cell scavenger receptor 2,SCARA4,Scavenger receptor class A member 4,Scavenger receptor with C type lectin,Scavenger receptor with C-type lectin,SRCL
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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