Anti-Human/Mouse/Rat CASC3 Polyclonal Antibody

The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12451
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CASC3
Specificity Widely expressed. Overexpressed in breast cancers and metastasis, as well as in gastric cancers.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O15234
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Barentsz,Barentsz protein,Btz,Cancer susceptibility candidate 3,Cancer susceptibility candidate gene 3 protein,CASC3,CASC3,Metastatic lymph node 51,Metastatic lymph node gene 51 protein,Metastatic lymph node protein 51,MLN 51,MLN 51 protein,MLN51,Protein barentsz,Protein CASC3,Protein MLN 51
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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