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Anti-Human/Mouse/Rat ARHGEF25 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
GEFT,also named as p63RhoGEF,may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01983
Size 100μl
Host Type Mouse
Immunogen Fusion protein of GEFT
Specificity Isoform 1 and isoform 2 are highly expressed in excitable tissues, such as brain, heart and muscle. Also detected in kidney and liver.
Isotype IgG2a
Reacitivity Human,Mouse,Rat
Clone 934
Uniprot Q86VW2
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names ARHGEF25,ARHGP,GEFT,Guanine nucleotide exchange factor GEFT,p63RhoGEF,RAC/CDC42 exchange factor,Rac/Cdc42/Rho exchange factor GEFT,Rho guanine nucleotide exchange factor 25,RhoA/RAC/CDC42 exchange factor,RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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