Anti-Human/Mouse/Rat AKR1D1 Polyclonal Antibody

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12993
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human AKR1D1
Specificity Highly expressed in liver. Expressed in testis and weakly in colon.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P51857
Concentration 0.1 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names 3-oxo-5-beta-steroid 4-dehydrogenase,3o5bred,AK1D1,AKR1D1,aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase),Aldo keto reductase family 1 member D1,Aldo-keto reductase family 1 member D1,CBAS2,Delta(4) 3 ketosteroid 5 beta reductase,Delta(4) 3 oxosteroid 5 beta reductase,Delta(4)-3-ketosteroid 5-beta-reductase,Delta(4)-3-oxosteroid 5-beta-reductase,SRD5B1,steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1),steroid 5 beta reductase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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