Anti-Human/Mouse PTEN Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]

PTEN (also designated MMAC1),products of tumor suppressor genes,are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors,such as brain,breast,kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA02102
Size	100μl
Host Type	Mouse
Immunogen	Fusion protein of PTEN
Specificity	Expressed at a relatively high level in all adult tissues, including heart, brain, placenta, lung, liver, muscle, kidney and pancreas.
Isotype	IgG2a
Reacitivity	Human,Mouse
Clone	45
Uniprot	P60484
Concentration	None
Dilution	WB 1:1000-1:10000, IHC 1:200-1:1200, IF 1:20-1:200
Formulation
Application	WB,IHC,IF,ELISA
Other Names	10q23del,BZS,DEC,GLM2,MGC11227,MHAM,MMAC1,MMAC1 phosphatase and tensin homolog deleted on chromosome 10,Mutated in multiple advanced cancers 1,Phosphatase and tensin homolog,Phosphatase and tensin like protein,Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN,Pten,PTEN,PTEN1,TEP1
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse PTEN Monoclonal Antibody

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