Anti-Human/Mouse MEST Monoclonal Antibody

MEST(Mesoderm-specific transcript homolog protein) is also named as PEG1 and belongs to the AB hydrolase superfamily. The gene is a imprinting gene,which is associated with growth of mesodermal origin cells and plays important roles in embryo development. It is also a novel regulator of Wnt/CTNNB signalling during adipogenic differentiation. It has 3 isoforms produced by alternative splicing and the full length protein has a glycosylation site.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02036
Size 100μl
Host Type Mouse
Immunogen Fusion protein of MEST
Specificity Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.
Isotype IgG2a
Reacitivity Human,Mouse
Clone 39
Uniprot Q5EB52
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500, IF 1:50-1:500
Formulation
Application WB,IHC,IF,ELISA
Other Names DKFZp686L18234,EC 3.-.-.-,Mesoderm specific transcript (mouse) homolog,Mesoderm specific transcript homolog (mouse),Mesoderm-specific transcript homolog protein,MEST,MEST,MGC111102,MGC8703,OTTHUMP00000210362,OTTHUMP00000210364,OTTHUMP00000210367,Paternally expressed gene 1,Paternally-expressed gene 1 protein,PEG1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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