Anti-Human/Mouse MAP2K6 Polyclonal Antibody

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12434
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human MAP2K6
Specificity Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P52564
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Dual specificity mitogen activated protein kinase kinase 6,Dual specificity mitogen-activated protein kinase kinase 6,MAP kinase kinase 6,MAP2K6,MAPK/ERK kinase 6,MAPKK 6,MAPKK6,MEK 6,MEK6,Mitogen Activated Protein Kinase Kinase 6,MKK 6,MKK6,MP2K6,PRKMK6,Protein kinase mitogen activated kinase 6,protein kinase,mitogen-activated,kinase 6 (MAP kinase kinase 6),SAPK kinase 3,SAPKK-3,SAPKK3,SKK3,Stress-activated protein kinase kinase 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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